Anti Hair Loss
(Tropical)

TRICHODERM®BlackSeries

Intensive Reactive Serum
Treatment Shampoo

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Anti Hair Loss
(Act Inside Out)

HGP

TRICHODERM®BlackSeries

Intensive Anti-Hair Loss Oral Supplement (Drug-Free)

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Grey Hair Reverse
(Tropical)

TRICHODERM®BlackSeries

Anti-Grey Hair Treatment Shampoo

What Are Stem Cells

Stem cells have the “self-duplication capability,” a function to divide and make copies of themselves, and the “differentiation capability,” which is a function to make various types of cells.

It is the work of the stem cells which helps to maintain our bodies healthy and heal wounds. Stem cells renew and aid the regeneration of all other cells in the body – including those of the skin, nails and hair. These regenerated cells are called adult stem cells. They reside in some adult tissues only.

Recently in the medical field, research has been active on “regenerative medicine,” which utilizes the stem cells to repair illness- and injury-damaged organs and tissues.

In 2009, a research team at the University of Toronto discovered a therapeutic application for restoring hair growth in those suffering from hair loss (alopecia)—and in those combatting the underlying causes that lead to the telltale signs of a damaged scalp. Their research was in the area of adult stem cells.

Two Types Of Stem Cells In The Scalp Tissue

There are two types of stem cells – “dermal stem cells” and “epidermal stem cells.” Each type has its own role.

Dermal Stem Cells
Epidermal Stem Cells
Location
In dermis (deep seated under the epidermis), localized at the base of the hair follicle (dermal papilla)
In epidermis (on the scalp surface), the hair bulge forms a reservoir of epidermal stem cells.
Function
Generate fibroblast, has the property to grow in colonies in the form of spheres. Support dermal rejuvenation and generate hair follicle formation and stimulate hair follicle formation and hair growth. Dermal stem cells that serve to induce hair morphogenesis and maintain the dermis.
Continue regeneration of the hair follicle during cycling. Has an important role in hair cycle turnover process, from anagen, catagen to telogen.

Hair Scalp

TrichoCell™ Deep-Seated Self-Regeneration Technology

Get to the root of thinning hair and hair loss by stimulating the activity of self- renewal dermal stems cells in the dermis to induce hair follce formation and at the same time stimulating the self renewal at the epidermal layer to prolong the life cycle of the hair.

Epidermis

Epidermal stem cells in the basal layer continuously regenerate the epidermal layer.

Dermis

Dermal stem cells confer firmness and elasticity to the skin and are involved in wound healing processes.

Hair Loss And Stem Cells

Hair Loss Issues

Hair Loss Issues: Dermal Stem Cells and Epidermal Cells

When suffering from hair loss, the telogen phase is prolonged, and the transition to the anagen phase becomes more difficult. Hair become thinner and the percentage of hair transitioning to the telogen phase continues to increase.

The problem comes from the fact that the hair follicle stem cells (also called ORSc) located in the bulge along the hair, are less productive, and less adapted to improve the quality of the matrix (made of keratinocytes) supporting the hair follicle growth. Furthermore, the fibroblasts located in the dermal papilla (also called HFDPc) are less efficient in communicating with the stem cells, meaning that the matrix will not be renewed as it used to.

Initiating the anagen phase becomes more sluggish, and hair loss becomes a part of daily life.

Telogen Phase

When the telogen phase is prolonged and the transition to the anagen phase becomes more difficult, extended hair loss occurs.

Hair becomes thinner. The percentage of hair transitioning to the telogen phase increases.

This happens when hair follicle stem cells, also called ORSc, become less productive, less adaptive to improving the quality of the matrix that supports follicle growth. This matrix is made of keratinocytes. Furthermore, the fibroblasts located in the dermal papilla, called HFDPc, are less efficient in communicating with the stem cells, resulting in the matrix no longer renewing as it used to.

Thus initiating the anagen phase becomes more sluggish, and hair loss becomes an eventual part of daily life.

Hair Loss

Hair loss is caused by a number of factors, including

Men

  • Physical and emotional stress
  • Endocrinopathy
  • Oral medication (blood thinning agents, antihypertensive agents, etc.)
  • Local impairment of circulation due to tension in the scalp
  • Reduction in physiological functions of the scalp
  • Reduction in hair follicle function due to male hormones
  • Reduction in metabolic functions of hair follicles and hair bulbs

Women

  • Aging
  • Medication (e.g. contraceptive pills, steroid, etc)
  • Postpartum period
  • Hormonal imbalance e.g. thyroid
  • Menopause
  • Under pressure and stressful lifestyle
  • Chemical hair product, over perms or dye

Hair Loss: By The Numbers

Men
Women
110,000 Hair
Average no. of hairs on a global surface of 600cm2 in the human scalp
Average no. of hairs on a global surface of 600cm2 in the human scalp
50-100​ Hair
Scalp hair lost each day
Scalp hair lost each day
25%
-
Percentage of women has thinned hair
40%
Percentage of men with noticeable hair loss by age 35 (this reaches 65% by age 60!)
During menopause, 4 out of 10 women suffer from thinning hair
95%
-
Percentage of female hair loss results from hormonal changes, as in pregnancy or menopause

Men

Hairs
Average no. of hairs on a global surface of 600cm2 in the human scalp

50-100

Hairs

Scalp hair lost each day

%

Percentage of men with noticeable hair loss by age 35
(this reaches 65% by age 60!)

Women

Hairs
Average no. of hairs on a global surface of 600cm2 in the human scalp

50-100

Hairs

Scalp hair lost each day

%

Percentage of women has thinned hair

%

Percentage of female hair loss results from hormonal changes, as in pregnancy or menopause

%

During menopause, 4 out of 10 women suffer from thinning hair

Role Of Plant Stem Cells

Role Of Plant Stem Cells

Plant stem cells protect skin stem cells.
How does this work?

Every stem cell contains specific epigenetic factors whose task is to preserve the stem cells’ multi-potency and its ability to self-renew. Applied in the right way, they have a positive impact on the vitality of skin stem cells and their proper functioning. Plant stem cells contain similar epigenetic factors as human stem cells.

Plant stem cell extracts provide important nutrients to human stem cells

Plant stem cell nutrients improve the viability and healthiness of human stem cells

Applied in the right way, they have a positive impact on the vitality of skin stem cells and their proper functioning

Plant stem cell extracts provide important nutrients to human stem cells

Plant stem cell nutrients improve the viability and healthiness of human stem cells

Applied in the right way, they have a positive impact on the vitality of skin stem cells and their proper functioning.

Stem Cells And The Hair Scalp

A New Way To Treat Hair Loss

Today, strong evidence demonstrate that the hair bulge forms a reservoir of epidermal stem cells. The dermal papilla not only regulates hair follicle development and growth; it is also thought to be a reservoir of multi-stem cell lineages.